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The kidneys are vital to the body.

They regulate the blood’s volume, pH levels, and pressure. They prevent the build-up of harmful toxins. They produce hormones that are vital to the circulatory and skeletal systems. So when your pet’s kidneys aren’t functioning properly, it can create a world of adversity for both you and your pet.
One popular supplement used to treat pets with azotemia is Azodyl from Vetoquinol

Azodyl® Effectively Treats Dog Kidney Failure and Cat Kidney Failure

Azodyl® Effectively Treats Dog Kidney Failure and Cat Kidney Failure
Azodyl ® contains a patented formulation of naturally-occurring “friendly” bacteria that are released in the large intestine, where they “eat up” uremic toxins and carry them out with them as they pass out of the body. Easy-to-administer, enteric coated capsules. Azodyl® can be used with other renal treatment and support products in the care of dogs and cats. Ask your veterinarian if Azodyl® is right for your pet. Always follow your veterinarian’s instructions.
Azodyl™ , for dogs and cats, is a mixture of three bacteria and a prebiotic with a unique mode of action that supports kidney function.
Azodyl is a proprietary formulation of beneficial bacteria that can be used to support normal renal health. Trusted for over 11 years, it is shown to help improve the quality of life.

Take care of what you love

Easy-to-administer, enteric coated capsules. Azodyl® can be used with other renal treatment and support products in the care of dogs and cats

How does Azodyl work?

This is a mixture of three viable bacteria that are strongly urease positive. This means they actively utilize the uremic toxins that diffuse into the bowel from the circulatory system thereby reducing the uremic toxic load.

FAQ

The capsules are intended to be administered as presented. Anecdotal evidence suggests that there is efficacy in BUN and creatinine reduction when the product is administered on the food. We are investigating: reduction of counts and BUN reduction if administered other than directed. These results should be available in a couple months. Best results are observed when administered whole.

The bacteria in Azodyl work best in the colon region of the intestine. The harsh environments of the stomach and small intestine are detrimental to the bacteria. Consequently, we have to encapsulate them to ensure the maximum number of bacteria reach the colon.

There are a number of studies. BUN and creatinine reduction has been observed in a pig model study. The results of clinical evaluation in client owned cats were recently reported in “The Journal of Veterinary Holistic Medicine”. Additional studies are underway.

Depending on the overall health state of the animal the reduction in BUN and creatine can occur as soon as two weeks but certainly we can see a reduction by the time of the next re-check (usually 1 month)

As these are viable organisms we recommend that it be keep refrigerated at all times. We store under refrigerated conditions and ship using coolers and freezer packs. our distributors keep it stored under those conditions. A clinical study showed that the bacterial counts were stable at -20, 4 and 25 degrees Centigrade (C) for up to 14 days. The counts decreased at 37, 45, and 55 degrees C. The urea hydrolytic activity remained at least at 50% even under the 45 degree conditions. We recommend refrigeration as we are concerned that there may be a cumulative effect of temperature elevations over time. These temperatures are: 4C=39.2 Fahrenheit (F), -20C=-4F, 25C=77F, 37C=99F, 45C=113F, 55C=131F.

We have no reported side effects except for a case of vomiting and two cases of diarrhea. These may be attributed to the concurrent CKD effects on the body. Re-establishing the normal gut microflora may have accounted for the upsets. If AZODYL is suspected we recommend reducing the does and continue observing the patient.

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